DOI: https://doi.org/10.7705/biomedica.v37i3.3189

Toxoplasmosis diseminada en un paciente con trasplante de corazón a pesar de la profilaxis con trimetoprim-sulfametoxazol

Victoria Dávila, Gustavo Roncancio-Villamil, Luis Alfonso Correa, Catalina Restrepo, Camilo Alberto Madrid, Javier Mauricio González

Resumen


Se reporta el caso de un paciente de sexo masculino, de 61 años de edad, quien ocho meses después de someterse a un trasplante de corazón presentó una enfermedad sistémica con compromiso del sistema nervioso central y del sistema inmunológico, así como de pulmón, riñón, colon y piel, y a quien finalmente se le diagnosticó toxoplasmosis diseminada, a pesar de haber recibido profilaxis con trimetoprim-sulfametoxazol, debido a que el órgano provenía de un donante positivo para toxoplasmosis siendo él un receptor negativo. Se discuten las opciones de profilaxis en nuestro medio.


Palabras clave


Toxoplasmosis; heart transplantation; immune tolerance; seroconversion

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Referencias


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Revista Biomédica -  https://doi.org/10.7705/issn.0120-4157
ISSN 0120-4157

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